Istradefylline forty mg/working day amplified peak levels and AUC of CYP3A4 substrates in clinical trials. This effect wasn't observed with istradefylline 20 mg/working day. Consider dose reduction of sensitive CYP3A4 substrates.viloxazine will boost the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Cauti… Read More